inflammatory

Inflammatory Markers

changes rapidly in response to inflammatory stimulus starting to rise in 4-6/24 and peaking in 36-50/42
half life 24/24
need to be interpreted in context and trending results are more important
high levels usually associated with:
- acute infections
- malignancies
- myocardial infarction
- pancreatitis
Persistent elevation associated with chronic inflammatory conditions:
- chronic infections eg bronchitis or hepatitis
- inflammatory arthritide eg. rheumatoid arthritis
- Systemic inflammation eg RA, SLE, other autoimmune diseases
Minor elevation seen with many conditions:
- obesity
- pregnancy
- depression
- diabetes
- cardiovascular disease.

NLR	Interpretation	Conditions
0.1-0.7	Neutropenia
1-2	Normal
2-3	Mild inflamm	autoimmune chr disease malignancy psych disorders Covid CVS disease diabetes
3-7	mild to mod inflamm
7-11	Mod to severe	Sepsis severe Covid SIRS
11-17	severe inflamm	Sepsis, SIRS, bacteraemia
>17	Critical inlamm	septic shock trauma advanced malig post-op

Author: Dr Dylan Jenkins, Oct 2023