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Acute Kidney Injurey (AKI)

Definition

NICE guidance AKI

  • rise in serum creatinine of 26micromol/litre or greater within 48/24
  • 50% or greater rise in serum creatinine known or presumed to have occurred within the past 7/7 NHS AKI algorithm
  • fall in urine output to less than 0.5ml/kg/hour for more than 6/24 in adults and more than 8/24 in children and young people
  • 25% or greater fall in eGFR in children and young people within the past 7/7.

Potential causes of AKI

  • Volume depletion
  • Sepsis
  • Medications which could be injurious to the kidney
  • Obstruction
  • Contrast Agent
  • Intrinsic Renal Disease
  • Rhabdomyolosis